One day 52 gr Berger 4 antelope between 65 and 630 yards with two 22-250s, closest shot through the point of the shoulder hard quartering on buck, only bullet caught on off side. Two mid range through the lungs, short sprint golf ball exits, longest behind the shoulder little smaller exit lungs still messed up.
8 Deer in about half an hour 52 gr vamax out to 600 yards, all clean kills, extreme evidence of broken blood vessels beyond jellow lungs no exit.
Another two deer, heavier mule deer between 300 and 320, 52 gr Berger, blown lungs, buck taken through the shoulder.
Running cow elk at 300 through lungs, piled up inside 100 yards.
5+ elk 223 with partition all inside three hundred, one round through lungs, 3/4 exit, dead elk inside 100 yards, one 320 class bull.
Multiple mule deer bucks with 223 out to 300 through the shoulders, dead inside 30 yards.
Based on experience with slower twist 22 cals, the newer fast twist heavy for cal will be sweet!