How does the 22-243AI stack up against the 22-284? Building one on a defiance today. With a 7 twist bartlein 29" to shoot the 90 grain berger.
It does very well, and in some ways, even better. The 22-284 is too overbore, and often, it requires more powder to obtain the same speeds as even a 22-250 AI. Let alone the 22-243 and Cheetahs, and the throat erosion issues tend to be greater with the 22-284.
Many 22-243's with a 26 inch tube can obtain 3,500 - 3,600 fps with 80 gr bullets, and many reach 3,300 fps or a touch higher with 90 gr Bergers. YMMV as these are fairly max. So, I would suspect your 29" should be able to get into that area, but even a 3,100 to 3,200 fps load will make a very good 1,000 yard and beyond load.
Given the ubiquitous 243 brass, it is much easier and cheaper to obtain then the current state of 284 brass, so that is another plus for the 22-243. In my humble opinion, the 22-243 versions are about the top end for the 22 bore, and even with that, I have mostly reverted back to 22-250AI's for most long range 22 bore work.