I need always ask the guide the 'Average " range at which the Mule Deer / Antelope are shot. Then YOU need to know your bullet, the weight , The BC, the velocity, and the energy at the range you will most likely be hitting the animal. On a Mule deer hunt in 1980, way before I had any understanding of a ballistic App, I simply had my .270 Weatherby Mag, with a 130 Grn Sierra GK, at 3300 /3325 fps zeroed at 300 yards for that hunt since the outfitter said many deer are taken between 300 to 400 yards. So, I was 3 inches high at 100 yds , 4 inches high at 200 yds , Zero at 300 yds and 7 inches or so low at 400 . So for the longest shot I expected to have, hold the cross hair on the back. As you can see there was no science here. Today, 100 yard zero, Memorize my 200 and 300 yard drops, if I need a faster shot, at a moving deer, but generally use the turret and adjust MOA based on ranger to the target . That is the most precise, IF TIME PERMITS !!!! ( I never, ever get the deer that pose at 200 yards, Like on TV. )