I've harvested on Idaho bull moose w/the 270 Win.
He wasn't the largest moose on the mountain coming in at 400 pounds, 4 qtrs hanging in the butcher shop.
It took awhile but he ended up harvested.
First shot @ 60 yards w/130 Sierra BT @ 3190 MV. Complete penetration with vigorous dust on off side hill side. Bullet expanded well taking the top off the heart.
Second shot, about 5 minutes, seemed like ages, again at 60 yards. This time through both shoulder blades about 2" above the joint.
That one slammed him.
Pretty amazed that nothing happened with that first shot.
Next time I go after a moose it's gonna be 5 shots. First in the boiler room then one for each knee. Then I'll tie the sucker to an aspen and use the pistol to finish.
They aren't hard to kill but some time take a long time to expire...