I am just getting into rifle shooting/hunting and have my 7 Rem Mag at a 100 yard zero. The elk outfitter I am using this season recommended a 300 yard zero but I'll need to find a public range that can accommodate that here in Central Florida. We have plenty of pistol ranges but finding a place to set up and practice with a hunting rifle is proving difficult. It sounds like a 100 yard zero isn't a terrible option though--really enjoying this forum.
There really is no need to actually sight in precisely at 300yrds if you know the velocity and the BC of the bullet you are using.
With most 8" MPBR (maximum point blank range) trajectories with a velocity over 3000fps, a sight in @ 100yrds of a 3" high impact is in the ball park for everything other than varmints. Even a 2.5" high zero @ 100yrds will give you a centre hold to 300yrds.
Some prefer a 10" MPBR for large deer or elk/moose, but this can hamper mid range and shortrange shots because you overshoot the target, causing a high miss.
Also, a trajectory that has the bullet rise 5" above the line of sight will cause a huge overshoot when shooting uphill or downhill, you would have to aim so far BELOW the animal to connect with it, that most people don't compensate enough and shoot high. Even a 15 degree angle will cause an overshoot with a centre hold @ 250yrds.
This where KNOWING your trajectory, sight in height and angle shooting affects are compulsory to study.
All hunters should have a ballistic program/app so they can see, then shoot to see they coincide, before shooting at game.
I use Ballistic AE on my Iphone and it is right on giving me my dopes once it's calibrated.
Cheers.