What I see consistently in this post is we have a range that we shoot comfortably at home in ideal situations. However, on live animals, in real time hunting conditions with wind, angles, heart rate up, etc, we need to dial that back many hundred yards so that when we pull the trigger we know that bullet will arrive as intended. I do not like the idea of hunters "trying" a long shot on an animal -
Trying long shots is for rocks and targets, long range shooting takes lots of time behind the gun and just as much time doping the wind. Wind will get you every time.
My long range hunting distance runs 400 to 700 yards with animals from Antelope, Bear, Deer, and Elk shot at those distances. I heard it said one time, "practice at twice the distance you are willing to take a shot in the field and that will improve your technique and accuracy."