Ok, I just did the math using trig and similar triangles...a 45 degree cant on the rifle, assuming a scope height of 1.75" and a 200 yard zero would result in horizontal error of 3.7" at 800 yards - no thanks. A 10 degree rifle cant (with the scope reticle leveled) would result in a one inch error at 800 and a 1.5" error at 1200. Not huge, but if you are trying to hit a ten inch plate at 800 and only shoot 4 inch groups, you are giving up 1/3 of your allowable wind call error 50% of the time (the other 50% you increased it by 1/3). And in real life, after practicing, you might think you are seeing spin drift and learn to compensate.
So I will concede not as dramatic as I thought.
Again, this is for the reticle level but the rifle canted.