Because of the freebore in a Weatherby my load maybe low but in my .30-8mm (almost the same as a .300 Weatherby for capacity) I shoot 76grs of R-22 with 210gr Matrix VLD's @ 3100fps seated about .030" off the rifling. My ES was 8fps for 3 rounds the last time I ran it across the chronograph. I would shoot for ES's below 20. In my rifle the Bergers aren't as accurate as the Matrix bullets so you might order a box and try them if you can't get the Bergers to shoot. Custom Rifle Bullets Built for Accuracy | Matrix Ballistics