First thing is to get a good bedding and barrel float. If it's a factory Remington barrel, if it's like the ones I've had, it coppers like all get-out. I've got a 300WM Sendero which shoot .3-.5 MOA for 20 rounds then opens to 2 MOA quickly. A full copper cleanout and it's back to being accurate. I did the Tubbs bullet treatment, the 3 finest sets skipping the two coarsest, and now I can get 40 rounds. Any custom barrel I have I never encounter these issues under 100 rounds.