Gingerman, you read the data on the Heat Index chart, then do your own testing over time in barrels you shoot keeping some good records.
A. leade growth per 100 rounds or even 50 rounds. Get ready for a shock if you are using Hot burning powders on the heat index chart such as N500 series.
B. Velocity drops as your throat grows in both length and diameter. You can measure the dia in throat growth with a Grizzley Rod from PTG and an oversize set of reamer pilots. As a baseline, in high-quality barrels, the bore dia is uniform to 0.0001 from end to end. As your velocity drops, add a tad more powder, maintain the distance from the lands that the bullet liked when the barrel was new, or re-barrel.
C. shots 4-10 in a string increase throat wear exponentially if done on a hot barrel, this is an expensive lesson to learn, measuring throat length wear range trip to range trip where you may fire 35-50 rounds per trip.
I have my own rifle range, shoot and reload at the range. With just a tad bit of record keeping, it seems that the manufacturers made certain powders just to eat barrels up. I could give examples, but it would just bore the heck out of you. Some things you just have to have "hands-on experience" to learn, and in the end, gained performance from really hot burning powders may be a good trade-off. We all have varying amounts of disposable income to invest in new barrels, some more than others.
Often, if you start off with enough Shank or "straight" on the back end of the barrel, you can set the barrel back. I found that with the hot burning powders, often 4-9" had to be cut off to get back to where the bore dia would be the same at the muzzle and throat.
IN my 7/08 AI, I will use AA2700 and HV100 first, as they burn extremely cool. I have shot cases of AA2700 with CCI 250s in my 243 AI over the years with very hard use on varmints, like dumping out a box of 50 and firing as fast as I can single load and pull the trigger. Barrel setbacks are around 1800 rounds with .070 freebore growth. Setbacks run 3/4" on the first, 2" on the second and third, then 4-6" on the fourth, barrel starting at a 30", Hart barrels, with a barrel ending up a 6 BR on the 4th chamber, 12 twist.
The first powder I used was IMR 4064 which wiped out 6" of the barrel in 2000 rounds, then IMR 4350, about the same as 4064. Winchester 760 was the first real change in seeing much less throat wear, then switched to AA2700(cooler burning yet). CCI 250's got the SD down below 9 fps. This is just one example as we found the same thing in the 22/250 AI with 12T with 55s at 4150 fps, 223 and 223 AI with 748 and H335 get incredible barrel life, but when we had other barrels we shot H322, AA2015, Benchmark, LT35, the leade just walked out much faster, not to mention the carbon in the barrel was cooked on to a greater degree.
The fastest barrels I ever shot out were with R#15 in a 22 BR, 220 Swift with N550, 22/250s with IMR 4064 & Varget, 243 Win with IMR 4064 and Varget, and 6 Remington with IMR 4064.
For guys that work up loads for a new rifle(big game hunting), verify zero from year to year, it would take a lifetime to fire 500 rounds, so you have to keep things in perspective.