Yes, my dogs have been quilled over the years. A vet had to be involved in most cases.
That said, I'm kinda neutral on shooting porcupines. That means I don't care either way. If they are within 1/2 mile of our camp, I'll always shoot them. They have girdled enough trees already.
If I'm hunting an area away from camp, I'll often leave them to a fisher, or another hunter. At our camp I'll put the dead porky in an open area, belly up. Most often there is near zero left after 2 days, scavengers appreciate the meal.
I've been with youth hunters that enjoy shooting them. My usual favorite gun for such is a 17 HMR, one shot is enough.
If I had cattle, like pictured above, yeah, I'd want them gone.