I have been shooting a 7mm Express for 40 years off and on, (it is called the 280 today & before being renamed to 7mm Express in 1978 or 79 I believe, it was a 280) Since that time I have built a few 308, 30-06, 7mm Mag, 300 WSM, and have had great results from all of them. My distances were 50yds to 150 yds, today that has stretched out to maybe 500 yds. Last year I took a muley at 250 yds with my 300 WSM and a whitetail at 70 yds in Nebraska. I was using a 180 gr Nosler BT and it did its job on both of them.
Today I am building a 300 WM, Remington 700, 30 cal 26" Douglas air gauged barrel, and a brake. I decided to build the 300 WM because I had a 458 Win Mag in the vault for a planned hunt to Africa 20 years or so ago, no I didn't go, so I finally pulled that barrel off it to build the 300 WM. I installed a factory 24" barrel but I want more speed so that's why I'm getting a new barrel.
The 300 WSM does great but I want to use some of the newer long bullets that are available for reloading and because my 300 WSM is in a Remington Model 7 the 180 gr is about all I can stuff into the magazine box.
The barrel is ordered and I'm waiting on it. I have all the other components ready to go when the barrel gets here. All I have to do is set the headspace if it's not correct, time the brake, and I'm ready to go.
I've been on this site for over a year and the most talked about build is a 300 WM imo because of the bullet choices if you reload or available ammo at the store if you don't.
Good luck with your build and choice of caliber.