One thing to consider is the reticle. I am moving more towards simpler reticle then having 10,000 lines in my line of sight on my hunting guns. And virtually every scope maker has their version of these, but (and I just screen captured 2 from vortex) but for my 280 AI (good choice by the way!!!) I have a simpler reticle because it can be used in the bush and if I'm shooting at distance I dial in both windage and elevation.
I have seen guys miss running deer because they didn't know which line they were looking at when pulling the trigger. At about 250 yards, the one guy realized he was looking at the 600 yard line kind of thing. Lead wise he was perfect for a fast walking deer... elevation wise he need to let that deer walk for another 15 minutes at least!!