Well if your not stuck on a 100grn bullet, I would suggest the 105 A-max or 107SMK. Most of the new rifles in 6mm have a tight enough twist to handle them. These 2 bullets with a good healthy dose of H4350 will achieve your objective. Here is an article that will help you out.
243 Win Cartridge Guide within AccurateShooter.com
I think the caliber you want will do all you need. One of the BOTW clips you can find on line shows them dropping a yote at 1100yds with a 243 using a 107SMK.
Tank
none of the NEW factory rifles that i know of have a twist fast enough for a 107 except for the savage 6br in an 8 twist. i have never heard of a factory remington stabalizing a 107. the Botw shot the coyote 1017 yards with a 105 berger out of an 8 twist 243. i have heard some rems will handle the 105 a-max . sully you should be able to find something that will work in your VLS. enjoy.