With a long action and wanting something a little different and not wanting an ackley I would personally do a 6-06 with a bartlien 7.5 twist and shoot either 105 Berger's or 115 Berger's. The heavier bullets will kill stuff just as dead as the lighter bullets. I don't have a 6-06 but when my 25-06 barrel is done I'm building a 6-06 improved.
Now you're talking long action far and away slam dunk I'd go 6/06 with a 7.5-8 twist on it. I ran thru two 6/06 barrels and it was one incredible beast of a killer