My thoughts are more along the lines that existing cartridges can be "improved" with different rifle configurations; faster twist, throat, longer barrels in addition to higher energy powders with technological advances in bullets. Plenty of good examples such as .270Win fast twist in long magazine actions to take advantage of its long neck to seat bullets out for more case capacity with newer powders like RL26. The venerable 30-06 is identical in opportunity for same exact reasons. The .280, .280AI, 25-06 all fall in same category. The key IMO is to use LA's with long COAL capability like 3.67 or longer to take advantage of the potential case capacity.
The HUGE benefit to these concepts is the brass is standard and readily available plus LR primers. I built my now absolutely favorite out of safe .270Win on 700LA, 27" Light Palma, 1:8, 0.290 freebore, 5R that delivered exceptional performance with 156HH at 3200 (topped out ~3300), 170EOL at 3100, 175TGK at 2925, even 160Part at 2900. I also saw great performance in 30-06 with RL26 with bullets seated out to max magazine capacity for jump. The potential is there for a lot of standard cartridges, all we have to do is build to take advantage of these cartridge's hidden potential.
Just my 2¢ on one cup of coffee.