I love the little ole 260 accurate cheap to shoot and with the 140 bergers bad medicine even on elk...this little gal is a former student of ours and killed this little bull at 525 and a cow at 670 with her "husbands" 260 we put together for him to take to NZ however I think she has adopted it
Out to about 750 with the right rig and a shooter who can put the bullet where it belongs I don't think there's anything other than big bears the little 260 can't handle in N. America.