From your OP the only constant that I can see is that your bolt will not close on your Ruger 77. You have received some really good suggestions to address your problem. One suggestion is to purchase some factory ammunition and see if that works in your rifle, if it does then we have a reloading issue, if the bolt still does not close then you have a rifle/headspace problem. I think it would be prudent, and less expensive, if you purchased some factory ammunition and go from there. If the new ammunition works in your rifle, then you'll have at least 20 new pieces of brass to work with. With all that said you really have to "isolate" the problem before you can fix it! If it were me and just starting out, I would suggest that all of your components are the same. The key to making good ammunition is one's ability to replicate every step within the reloading process; that means everything, especially when first starting out. The more extraneous variables that are introduced to the process makes it more difficult when one tries to diagnose a problem such as what you are presently encountering.
I would suggest, as others have, to (1) first start out by screwing your resizing die down until it just touches the top of your shell holder and lock the die in place with the locking ring, and full-length resize your casing. (2) I would put a resized/trimmed casing in your press, put the seating die in the press, raise the ram of your press with an empty casing up until the ram stops, and screw your seating die down by hand until it will not go down any further and touches the mouth of your brass, (3) then back the seating die off by a half to full turn and lock the seating die with the lock ring. (4) After resizing, priming and charging your brass, I would then, with my seating die locked and in place, seat a bullet to the recommended COAL (case over all length); Nosler Reloading Guide #8 gives a COAL of 2.710 for the .243 Winchester. THEN try your completed reload in your rifle, in a safe place. You could have a situation where your seating die is set too deep and you are creating a situation where you are crimping your case where it is bulging the neck or the casing body ever so slightly, where you cannot see it, and creating a situation where the cartridge case does not match your chamber. It really should not matter with the .243 Winchester, but just curious about what you are using for a press? The .243 is one of the easiest cartridges to reload. As previously mentioned, try to be as consistent and repetitive as possible. Also "if" at all possible if you could find a mentor to show you the reloading process it would be of a great help to you.