Many years ago when I started with my STW, I had a load of 83gr. of 7828 over a 140 gr Ballistic tip (first mistake), but it was before Accubonds were even made. 3560 FPS. At distance, the load was deadly, up close, almost useless. A good W.Va. buck came running past me at 35 yards, quartering up hill. I hit him in the closest shoulder and he went down, only to get up and attempt to leave to the next state. I hit him again and he did not get up.
What I found was unbelievable to me. The front leg and shoulder that I hit with the first shot was ripped off, just a hole. It looked like a bomb had been ignited just under the skin. Upon skinning the buck, nothing had penetrated into the chest cavity. I was shocked that there was nothing in the cavity. I never shot another Ballistic tip out of that rifle. The accuracy was in the .2 with that load, but with that velocity, the bullet could not be counted on.
Extreme velocity is tough on bullets. Use a bullet that can handle the velocity for sure. Back here in the east, it can be a shot at 25 yds or at 600yds on another ridge sitting in the same location.