I'd just view the barrel as a consumable at this point - if you shoot out a barrel, it means you had a lot of fun. There are plenty of prefits available that make replacing barrels very easy.
If more of a range rifle, the Seekins Havak Hit could be a good option to consider (chambers include 6 GT or 6 CM). Replacement barrels from Seekins are $500 and only take minutes to install.
For me - 6 CM is the easy button. But if strictly hand loading, you have plenty of options. Pick which one is easiest to obtain components for and go with that.