There are alot of factors to consider...factory barrel vs custom, barrel length, individual barrel, loaded cartridge length..... I say this because we have many reloading sources available to us today that are backed by pressure test equipment. If one is significantly higher than published data ( or something like quickload) for comparable testing, we may be over pressure.
All that stated, I will generally find what I consider max in my rifle using published data as a reference and other visual and tactile ques ( sticky bolt, primer shape, ejector swipe, case head expansion, etc...). I will generally go back and verify this at least once during load development and at the earliest confirmation, I will stop, pulling bullets from rounds above this point.