another different take on this, I've run the eld-x at reasonable velocities too. I've killed a couple medium game with them using rib/lung/heart shots. they all die. bullet appears to have worked well. I'm sure there are other people here that have broken down a large brown bear. There is not reasonable comparison to the bone and muscle structure of a deer/elk to a large brown bear. the bones are exceptionally heavy and strong. the muscles are tightly bound and very dense on their own.
at 200yds from my 260rem, the 143 eld-x fragmented on a caribou rib bone. That speaks to the overall construction of the line. a bullet with that style construction will most likely splash on a bear shoulder. The bone may break, but I wouldn't put any money on that bullet doing terminal damage.
Don't be a jerk and use lightly constructed bullets for dangerous game. you won't follow that bear into the alders when it's wounded and ****ed, your guide will. ask them what they use, it's not going to be en ELD.