Yes they will work if you can find a load on the slow side, the 6 mm br produces pretty high pressure and the mag. primers provide a little safety against possible piercing plus better SD's are common with the 450's over 400'sWorking at getting components for my wife's 6BR. Found 8 Lb of Varget Lapua brass and Lapua 105's.was able to score some CCI 400 primers today on Powder Valley. It seems like most load data calls for BR4 or 450's. Will these work ok?