You underestimate how effective the 110-115gr bullets are on deer out to around 350 yards or so. Small entrance, small exit, very little meat damage, but with warp-speed velocities like the .257 Roy and .25-06AI, they leave a massive wound cavity, from expelling all their energy, but retaining enough to cause a clean exit.
My first trip out with the .257 Wby I dropped a big doe at around 100 yards or so. She ran about 30-40 yards and dropped. Took it to my buddy who owns a deer processing business, and he cut it open and said he'd never seen such massive soft-tissue (vitals) damage with virtually zero meat damage. That was in Jan of 2009. I asked him last year if he'd ever seen anything like it since, and he still says he has not. Said it still baffles him.