I have been running the 168 TSX @ 3340fps out of my 300 rum for several years. Moose, bears, and caribou have all fallen to this load. I've yet to recover one and the accuracy and penetration is outstanding. I have never stopped one in an animal and that includes a stem to stern shot on a bull moose at 200 yards, we're talking 5+ feet of penetration. I switched to 168 TTSX a couple years ago looking for a little more expansion. So far I have used the TTSX on caribou and moose. A moose at 225 yards, high shoulder/spine shot. Broke a lot of bone and still punched out the far side, crumpled the bull in his tracks. I shot a large caribou at 519 yards, text book expansion and penetration, destroyed the heart/lungs. Put two shots thru the boiler room.
One thing I have noticed about the TTSX and TSX bullets is that since you don't have the explosiveness of a conventional bullet that it doesn't havet the immediate shock value that would will get with a Nosler BT or Partition, but you get dependable wound channels and amazing penetration. For the bigger game that I hunt here in alaska this is very important. I also recomend stepping down in bullet weight. The 130gr TTSX is a very good bullet for the 308/30/06 rounds. I load the 130 TTSX @ 3100fps for my sons 308. I have no doubt that it will tip over a cow moose this fall. I have a buddy back in michigan who runs the 130gr TTSX out of his 300 RUM @ nearly 3900fps. It has proven to be a whitetail lightening bolt. He has yet to recover a bullet, and killed a ton of whitetails with it. It allows him a point and click simplicity out past 400 yards.
My rule of thumb is that a TSX or TTSX has be run over 3k fps. What ever bullet weight you need to use in a given cartridge to keep the speed up is what you have to use. The 110 or 130 in a 308, 130 or 150 in a 30/06, etc...If a cartrige can't get to 3000+ FPS I would use a conventional cup/core style bullet like a ballistic tip, accubond, or partition.
