Your first post after nine years as a member...wow...how did you remember your login? I wouldn't have had a chance to do that!
Len, that has got to be some kind of record!?
partisan1911 has good info there regarding gear and physical shape. Sounds like you should know a bit about both from your description. I think combining a background in multinight backpacking or climbing with hunting can produce some great results. If you've backpacked or climbed quite a bit, you'll be familiar with availabe gear and be able to hygrade the best stuff and leave the rest at home as an anchor traveling light and fast with just what you need. LRH bring enough heavy gear of it's own with optics (rangefinder, binocs, spotting scope and tripod) and typically a heavier than usual rifle, such that it is even more important to use the best gear. Gear that is rarely purchased from the likes of Cabelas, for instance...not to knock Cabelas, but it's name is not synonomous with light and/or fast when it comes to backpack hunting, for the most part. JMHO
Just make sure you have an appropriate shelter than can take a beating and keep you dry and never let your sleeping bag get wet--two among several of my mantras and probably two of yours.
Many here like the Eberlestock packs. This is the pack I use:
LongHunter Hauler Has a nice packbag that attaches to it or, make a packbag yourself. Custom made to you and you can haul stuff around and immediately be ready to haul all or part of an animal out with it. I've hauled out all of a nice 4pt Mule deer and bear this year with it already. Hauled several elk and another deer out over the years. Had if for 7 years I want to say and hauled a few critters with it. Hauls your firearm very nicely with the 'Gun Bearer'. From the sounds of your backpacking experience, you may know of the 'Mountainsmith' brand. Patrick Smith started Kifaru after he sold Mountainsmith, so he knows a thing or two about lightweight and functional--something many brands do not.
Patrick's shelters are also something else. Check out shelters on his website.
I ended up building my own tipi and used one of his stoves with a custom lenght stovepipe.
http://www.longrangehunting.com/forums/f61/tents-backpacking-26738/
I built in some venting, an attached floor and bugproofing that his tipis don't have. I like nature, just not the 6 or 8 legged kind crawling into my sleeping back with me at night. My 10' dia. by 7' tall shelter weighs 6.5 lbs and the stove (which drives us out of the tent at full roar), another 3 lbs. I use this setup for November elk hunting.
Anyway, better stop rambling here...but there's some ideas perhpas for you to consider.
Edit: You mentioned backpacking into the wilderness. If by 'wilderness' you mean a desginated 'Wilderness Area', it's not legal to leave stuff (like a camp) setup for any length of time you may not be there. Designated wilderness areas are the most highly protected recreational lands. Absolutely nothing mechanized allowed--the wheel on a game cart--mechanized--not allowed. So setting stuff up a few days before hunt won't cut it. Wilderness rangers have very little compassion for bending the rules at all in designated wilderness and they will throw the proverbial book at you. Just a note re a post above...