There is more to consider with big overbores than simple MV.
3,200 ft/sec was mentioned with 140s from the WSM case. I can get the same from a WSSM case, using way less powder.
The difference is pressure of course.
Pressure creates force as pounds per square inch (PSI). So with a given pressure, the forces exhibited with a WSM case area are a lot higher than those from a WSSM case area. That's why I can run higher viable pressures with the 6.5WSSM.
And choosing a high pressure load -vs- low pressure load is easy for me. I choose higher, for advantages of it -with a good plan.
That's my basis for a notion that bigger is not better.
For an extreme analogy of this, consider the tiny little 6PPC for point blank BR competition. It's an underbore.
Why doesn't anybody compete against it using an overbore cartridge?
Well, they could try, and they'll lose for sure.
A competitive 6PPC load runs up around 75Kpsi. This is viable (somewhat) because the case area is so small.
It's competitive because pressures that high are deep into diminished returns, which results in diminished variance of returns.
A 243Win can match same & higher MV easier -while shooting like a dog compared to a 6PPC.
Since I see accuracy as the most powerful of all ballistic attributes, I am not out for biggest velocity numbers.
I prefer more disciplined, logical, designs.
I know somebody out there is shooting 1/4moa regular with giant overbores, but I could never rely on the luck it takes to find that.