A 6mm Creedmoor barrel is usually completely done at 1100-1300rnds. A 22 creed is 1000-1200 typically. So barrel life is close enough to not be a factor. Ballistically, well the numbers are plain for those that wish to run them. The retained energy at normal engagement distances, and the likelihood of transfering that energy to the animal vs a pass through... is especially noteworthy. Regarding my own choices, the 22 creed and its versatility has rendered the 6 creed obsolete at worst, and non-essential at best. It is also noteworthy that I have never been able to get a 6 creed to shoot as tight as even my average 22 creeds. The best of my 22 creeds are literal one-hole rifles. Groups in the .1's.
Here is a 6mm 105 berger at 3150.
Here is an 22cal 80gr berger at 3500.