For what it's worth Sir, my son and I have both hunted in Nevada with rifles chambered in 6.5-284 Norma. We handload exclusively and I have never even seen factory ammo in that caliber. We've been really impressed with this cartridge both for its easy accuracy, light recoil and surprisingly effective terminal ballistics. We've hunted Pronghorn, big Mule Deer and Elk. If it's any help, we've stayed with Hornady bullets in the 140 (the old A-Max) and the 147 ELD-M and haven't ever had a single problem. Quick efficient kills have been the situation every time. A friend of mine who is a long-range competitive shooter recommended RL-16 as he's found it to be to be temp insensitive; and he obtained good accuracy and low ES numbers with it. It was his experience RL-16 was a tad slower than H4350 but certainly in the same ballpark. We did get great results at the upper end of pressures with that powder but, after tinkering around for quite a while, we've determined, at least in our 24" guns with long throats, that both H4350 and RL-16 are a bit too fast. I think you'll have better luck with slower propellants. H4831SC, H1000 and even Retumbo come to mind. We've hunted in sub-zero and 100+ degree weather here in the high desert, so we almost exclusively stick with the aforementioned temp. insensitive powders. Every gun, barrel, chamber, etc. is a bit different so I hesitate to post what powder charges we use. I believe the slower powders are sure to give you the velocities and accuracy you want. The slower fuels do fill the case up, for sure, but by long-loading our ammo that's been less of a concern. Best of luck to you and happy hunting!