In cut rifling and in chambering, an opposing land is desirable. We've done most of our data analysis with 5 vs 4 groove. We use 4 groove. When you get to 338 and up 6 and 8 may be better options.
There's some next-level secret squirrel stuff in play here. Maybe we'll make a video about it one of these days.
This doesn't mean good results can't be had with other configs, but there's a reason why many custom guns need to have a load workup to find it. We live in a different world. If our gun doesn't shoot our off-the-shelf ammo, we get to start over....