I appreciate all the responses and suggestions. After chatting with med358-boise, I'm starting to come around to the idea that shot placement had as much to do with my impressions of this bullet/caliber as the actual bullet. Coming from a traditional bow hunting background I have always just taken broadside double lung or heart lung shots. Both of these deer were taken with something closer to high shoulder shots. I'm still very impressed with both the reaction of the animal and the subdued reaction of the animals around the one that was shot. They startled, but only for a few yards or so before going about their business.
So I guess my questions are: a. At what speed will this bullet still have the same effect on deer with a high shoulder shot, b) are high shoulder shots more dependent on speed and pressure or bullet diameter and weight.
I've only shot three deer high enough to be close to the spine or nervous system and all three were with heavier calibers, 2 with the 358 and one with a 50 cal FTX, so I don't have much of a database to go on.