I would skip H380. It is VERY temprature sensitive and it is hard to get small extreme spreads.
BENCHMARK has worked well for me in the past. RL-15 is a kick butt 308 powder. Currently I am running VV-N540 and dont think I will ever look back. The accuracy nodes are VERY wide and velocity is staggering. Running the 168 AMAX at 2823 with room for more. 2823 is where the best accuracy is. Regularly shoots in the .2's and .3's 3 AND 5 shot groups.
For up to 600 yard lope and deer bullets, I recomend either the 150 ACCUBOND, 150,168 Ballistic tip or the 168, 178 AMAX or 190 Berger, or the 200 SGK. The 200 SGK will get you out to 750 yards on game and do it ethically. That is in standard air. You could take her farther the higher in elevation you go. Ethically meening you will have reliable expansion and over 1000 foot pounds of energy left.
Welcome to the 308 world!