The best advice I received when I learned to reload the 300 Wby in my MK5, is to seat the bullet out as far as possible, to the max length of the box magazine.
Make certain that when you load all three rounds in the box, that none will hang up.
My initial load was around 1 moa, took the above advice, it shrank to. 3 -. 4 moa.
Advice is only on Weatherby rifles with the freebore..
I also use a Lee Factory crimp die.
Over the years I have heard the same advice from many Wby reloaded, they too seen their groups shrink over 50% when bullets are seated to max.
Lastly, Fed 215 or 215M primers are highly recommended.
Good Luck