Over the last 30 years of hunting deer with a center fire rifle (various 270 Winchesters); I have had various speeds with the same load. 110 grain Speer Hollow point, AA 3100, WLRM, and Norma brass. I have had varied speeds from 3,410 to 3,590 FPS+. I no longer can get AA3100 which I loved and most of my 270 Wins loved. now I have to use H4350, H4831, and some other powders. I have not settled on a powder yet, but the Alliant Reloader series has never been good to me and my rifles. so I shy away from them. If you all want to talk temp sensitive powders, lets talk; the worlds worst powders for temperature sensitivity is Vihta Vuori out of Finland. That was the 270 Winchester powder everyone in my little town used. so I fell into that trap too. in the fall/winter you would formulate a good round, then in early season warm/extremely warm weather hunts you would see flowed back primers and pierced primers and holes cut in your primers. that is the difference between 45 degrees and 95 degrees with VV powders.
here is the load data I used for my 110 grain slugs with N-165 VV powders and my true velocity between winter and summer.
Speer 110 grain slug, 61.5 grains of N-165 powder (max was at that time 62.0, now 61.7), magnum Winchester LR primer, Norma cases.
My Ohler chrono stated 3,450 FPS, STD Dev. was 8 FPS. (45 degree day)
same everything but summer time (95 degree day)
Ohler stated the rounds were going 3,590 FPS. S/D was 29 FPS
I stopped using VihtaVuori powders.
My 270 Win and 270 WSM's love Hodgdon's powders, they like a Ramshot powder, they tolerate a precisely metered & weighed IMR powder or two.
The last time I used an Alliant Reloader series powder my gun would not pattern better than improved cylinder. I stopped using the RL powder and gave it away to a friend.