Sustained rate of fire is always the biggest barrel killer. Yes, if slower powders are used and if you can keep your finger off the trigger when the barrel is warm, it will last longer.
My first 6 comp match, the most comparable to 243 AI lasted 1800 rds, my 2nd barrel dumped pressure at 600 rds(both IMR 7977). I made a switch to H4831 got 600 more rds exactly and the barrel was toast.
I was not always this way, but barrel life means absolutely nothing to me today, I am going to shoot my rifles when and how I WANT to. I may have 2-3 blanks downstairs right now, but had up to 8 in waiting. You build a hot rod, no reason to race ford fiestas on a back road, go for the gold.