I just wanted to add that while the OP is discussing the .243, I've had similar experiences with the .270. Hydrostatic shock kills are a funny thing. When they happen it almost seems magical. It probably isn't realistic however to depend on them. Bottom line is that if you're a good enough rifleman to be able to hit the heart shot after shot (a relatively small target at distance actually) don't change a thing. Meat on the table every time. I did however discover with my .270 that a change in bullet significantly increased the percentage of hydrostatic shock kills to nearly 95% at ranges to 400 yds. I switched to Hornady 140gr BTSP in that rifle over 20 years ago and never looked back. Can't say if the same thing would happen for anyone else in any other caliber but they've given me the DRT performance the OP is seeking nearly every time. Just my 2¢ worth