Sorry for the very late response-thought I would post my experiences though. I have shot the Berger 95 gr VLD from my 243 AI (MV 3330 fps, 0.5" groups @ 100 yds). My hunting results are as follows: Antelope buck @ 512 yards, high shoulder, bullet exited, antelope dropped. Whitetail buck @ 430 yards, behind shoulder, did not recover bullet, deer ran ~25 yards and fell dead. I have no data on game at any closer ranges, other than friends reports. Currently, until I see otherwise, I would not hesitate to shoot a deer/antelope at closer range. I hope this helps.