i agree with twist reccomendation. I will say though maybe a fluke, my Rra with a 1in 8 LOVES the 50 grainer. 1/4 minute out to 500 and 600 on paper (nosler). Same thing with the Barnes 70. Did a review on the 70 at midway. Check it out. actually shot one at a touch over 300 facing me with the 70 Barnes. broke neck, traveled all the way through deer, destroyed vitals, exited out of right Ham. Quarter size exit wound. Deer camp as was I slack jawed at the performance of the bullet. The Swift because of the velocity may not act that way with both extremes in weight but the .223 doesn't care. Either way I wouldn"t shoot one much past 300now that I have better rifles for that. Longest shot with little bores was 380 yds verified by laser. Neck shot with F4 jacketed Benchrest bullets. Deer never knew what hit it. It was a bang flop affair with my Swift. I will say I now relegate my .22s under 200 yards, out to 5 i shoot my 6.5x.284, over 500, the 300 RUM is the stick of choice. I have often wished one of my 22-250s had a faster twist. i am really interested to see if the little pills can stand up to that velocity and twist. Good luck with your build and keep us posted 1 and 8 would be my choice. after re reading initial post i should have said pre barnes had no exit not that they didn't open. Trust me they opened. Like stuffing a hand grenade in the body cavity and walking away. 3900 fps is pretty amazing when it hits 90 percent water. You may want to read a little on P.O Ackley and his veiws of the .22. If plate armor cant stop the little pills how is a deer or hog? Interesting to know those old timers views if they had the copper pills around then. We might all have been singing a different tune much earlier in our hunting careers.