I have killed deer with Rem 22/250's with 14 twists
55g Hornady Soft point with the cannalure
63g Sierra semi point is very accurate in a 14 twist
New bullet out that is fantastic, the Speer 55g Bonded Core bullet, and it is very, very accurate!
55g use Varget
63g use IMR, H, or AA4350
A 64g Winchester may stabalize out of the 14T, I have read it but not played around with it myself.
65g Sierra BTSP will not stabalize in a 14T, nor will a 60g V max.
I have shot half a dozen deer with the rem 700 with the 60g partition, and groups are 2" to 1.5". If you hit a deer on the shoulder with this bullet, you will throw away the front half of the deer, MV of 3450 fps.