When a rifle "won't shoot" after a few prospective loads, say 1-2 projectiles, 1-2 powders with a 2-3gn spread in .5gn increments, it's time to pull the stock, scope, mounts, and start looking for mechanical maladies.
Things touching things they're not supposed to touch.
Scope-base screws on bbl tenon,
action screws bottoming out on the action before they tighten the action to the stock, or touching the stock somewhere in the hole
The bbl making contact w/the stock where it shouldn't to include flexing/vibrating contact during recoil
bbl'd action teeter-tottering on the recoil-lug and/or magazine, bottom-metal teeter-tottering on a high spot in the inlet.
Scope-rings with enough misalignment to torque the scope
The scope making contact w/the bbl.
Sling-swivel studs dragging on front or rear bags during recoil
Then the scope itself.
Get the mechanics right and you'll find a lot more of those "unicorn" rifles that seem to shoot everything well. Get them wrong and you can tinker until the world runs out of components.