I have 5 Savages and have always been a Remington fan. I have had such incredible success with my Savages that is what I look for and build from now. I have had several Winchesters over the years too but have no love or hate for them. Just prefer my Savages. Nice rifles, easy to tune, shoot great out of the box, etc.
The 260 10 Predator is a nice heavy rifle for LR shooting. The 260 will not keep pace the 264 WM though. An option would be to get a 6.5-284. It is in between the two for performance. I have 2 6.5-284 rifles in Savage 116 with the 24" varmint contour barrels. 1 is getting a 27 Snyder in March. I expect to be throwing 140's at 3000 fps with ease.
I think you will want something like the Sendero or the Predator, creed, 260, 264, or 6.5-284 all work well for med to LR. I use my 6.5 for LR wolf hunting.
Optics and Scabbards. You will want a good scabbard. I got one for our wilderness hunts and taking clients with LR rifles. LR optics don't fit standard scabbards well. I run a scopecoat made of 6mm neoprene and stuff it in. It is tight, but man, I don't want to mess up a 2000.00 piece of glass.
OK, on to glass. I have a NF, Leupold, and Sightron. My buddy has the Vortex. I like the vortex well enough I would highly consider it. The only complaint I have is eye relief is marginal, and the parallax and power adj are stiff. My sightron parallax is stiff too, but eye relief is better and the glass is just as good. Between the 2 I like Sightron a tad better but the Vortex is a nice piece and the warranty is hard to beat. So in my opinion the Vortex is a great choice.