Shot my first Elk and my second, third, and fourth deer (1st was with a bow) with a 3006 named Bertha. As the oldest son, Bertha is now mine. Before she was mine, she was my fathers, before that she was his fathers, before that she was his fathers' fathers, and according to family tradition she belonged to the US army before that (as my great grandfathers' service rifle in WWI). Bertha is a M1917 Enfield from the Eddystone Plant. My Grandfather cut off the front and rear sights, recrowned the barrel, added a scope mount, and put it in an aftermarket stock. My father had her glass bedded and put in a custom trigger. I put a Leupold VXIII and better rings on her, and Tubbs FF'd the bore. She is now a solid 1 moa rifle.
My wife killed her first, second, and third elk with Bertha as well as her second, third, and fourth deer, and several antelope. We are shooting 180 gr Accubonds with good results on elk and deer. On several occasions they have been able to go through one shoulder, through the chest cavity (lungs), and stop at the offside shoulder. So far the Accubonds from Bertha have not made it through both shoulders of an elk (wasn't necessary).