I've used both RL26 and H4350 in my 22" 6mm creed. The H4350 actually gets me about 50 fps more in this rifle before pressure - first time I've ever seen that compared to RL26.
Both shoot 1/2 moa, with the RL26 being a little more accurate in the loads I've found so far.
My current load is 42.4gr of H4350, 105gr Berger hybrids, CCI200, 20 thou off the lands. I've shot whitetail, hogs, coyotes and Antelope with it - it's a great all around caliber that's easy for kids to shoot as well!
Im a big fan