It all depends on what you are envisioning. I think with what you have now I would move to a 7mm or the 6.5mm. With the rum length action and magnum it depends do you want really long range, or something that will get the job done and not pound you. A good old 7mag or the new 7PRC probably would be better in the 24 inch length with a 1/8 twist. You said you don't hand load so probably the 7PRC. If 6.5 then 6.5PRC. Very good factory offering. Also don't forget about the 6.8 Western. I would narrow down what I'm actually looking for as for caliber, distance I want to kill something at, and does it have enough retained energy to make a bullet function at that distance. If going 300PRC also go with a 1/8. Then you will never worry about if you have enough twist to stabilize a 250atip. Even when shot out of the slower 300PRC the 250ATIP is one heck of a BC monster. I'm in the same boat somewhat between 7mm something but o really only have 2 choices 280AI or 7mm rem mag. Both will have a 26 inch barrel for me. The 280ai will be much easier on the action to setup I think. The 7mm will require a bolt face change.