Here's THE mother of all big game guide clusters.
A man from the 48 states was hunting brown bear with his guide on the west side of Cook Inlet, Alaska.
The client took a shot at a brown bear from a rested, sitting position. The shot reportedly hit the bear, and the bear heads for the alders at the far side of the opening. The assistant guide was standing behind the client. As the bear heads out for the brush, the guide shoulders his rifle and shoots to anchor the wounded and escaping bear. As fate would have it, the client rose to a standing position to get a better shot and took the the his guide's bullet to the back of his skull! Instant death of the client. So much for the guide tending to the well being of the client...
I kid you not! This happened about 6yrs ago. The assistant guide was from my home town, on Alaska's Kenai Peninsula.