Interesting,
When I was working up loads for my Friends .300RUM using 180g Barnes TTSX, I was actually using load data from Hodgdon, but for a 180g bullet, not necessarily a TTSX.
It listed the max loads being 100.5g of Retumbo, so I started at 95g and worked up to 100g and decided that 99g was the best and was certainly reasonable on the pressure aspect. Pressure Signs (stiff bolt lift, bras flowing int the extractor, etc...) started at 100g, but were non exhistant at 99g, so I backed it off 1 full grain. I must also add that these loads were worked up at 80 degree F and we did shoot the final loads over a Chrony. The 99g loads go 3400FPS.
As for seating depth, I just made them fit the magazine, I couldn't do much else as seating for accuracy would make the rifle a single shot, it has a generous throat.
These loads are safe in my friends rifle ( a Rem 700 BDL Synthetic, 26"bbl), I'd look at the Hodgdon web site as well as a few other sources and cross referance the data to see what is out there.
It certainly sounds like you're load is really light What is the Max load you're using???? That would certainly help.