I have shot quite a few antelope and a mature muley buck with them from my 6mm284. IIRC, my older Sierra manual says to run them up to 3300 fps, but I am running them at closer to 3400. They have a tendency to explode, splash and do some otherwise unpredictable stuff. I am guessing it is due to the velocity.
In one instance I shot an antelope doe right behind the shoulder, broadside. The bullet blew up so bad it punctured the gut cavity and made a disgusting mess of the inside.
I had another antelope that was slightly quartered towards me at 360 yards. I hit it in the near shoulder. A large piece of the bullet somehow made a turn and slid right down the spine, wrecking the backstraps.
On the muley buck the bullet splashed on the ribs right behind the shoulder. At first I thought I lost a lot of meat, but it turns out that the blood clots traveled between the meat layers clear up and over the back and part way down the other side.
On coyotes I have had some stellar results, but also a mess or two. At the velocity I am at the damage is pretty severe at times.
My opinion is that in a WSSM you should load them to run slower to get good results. I hear of tons of reports of guys using them in a .243 Win with satisfactory results. If you wanna use the full velocity potential of your cartridge, I would recommend a more heavily constructed bullet for dual purpose use.