So my personal assessment of where to set your zero range has got to be perfect for everyone else, no exceptions, regardless of cartridge used, thread!
Or my real recommendation just do your own thing, for your style of hunting, in your location, for the best outcome of your success...but there is no fun in that statement.
This is long range hunting, but I don't do that...mostly, just varmints for LR.
Bow hunting for 10 yrs, I went back to rifle, and shoot big game these days inside 100 yds, about one third on a dead run trying to escape. So I generally use big bullets in 338 mag and 350 mag. Sometimes 416 Rigby.
I like huge exit wounds, ...almost as powerful as Joe Bidens 9mm, that he claims will blow the lungs clean out of a person...should be great for the big game hunter too...his 9mm is probably sighed in for Moscow, Russia.