I have used 2x fixed and 4x fixed Leupold handgun scopes on a FA 454 Casull: load 300 grain XTP 1775 MV-with no problems at all.
All scopes brands will have problems from time to time.
One reason why scopes go down (besides a flaw from the factory or being exceptionally cheap) is because a person has taken either the elev or right/left adjustment to the point of being bottomed out. the mount system is not always properly aligned, some times becasue of the mount and other times because the holes are off.
If you run the adjustments all the eway to the end, it is does not allow the springs to work (Like loading a truck down till it is resting on its axles, then going down a bumpy or washboard road) and it will break.
Soon, I will be putting four different brands of variables on a FA Model 83 454 Casull. I will post the results when all is said and done.