I'm always the different one everytime this question is asked. I use RL22 exclusively in my 300WM. I use 75 grns. in Winchester brass lit by a Fed GM215M primer under a 180 grn. Accubond. The load was developed when it was 80 degrees and chronographed at 3148 fps. I haven't changed the load in 8 yrs. and I've never hauled a chrono with me when I'm out hunting. But I've killed elk out to over 600 yds. when it was below zero. So whatever velocity I lost was not enough to matter to those elk. I'm not saying it's not temp. sensitive, but it hasn't hurt me. However, you might have trouble if you work your load up when it's very cold out and then you go to shoot the same load during the summer and it's 90 degrees out.
You won't know how it acts in your rifle until you try.
I guess if you're that worried about it, you could go and chrono your rifle in different temps and figure out drop charts accordingly. Do it at maybe 80 degrees, 50 degrees, 20 degrees and 0 degrees and enter your info into your ballistic program. It would take 2 secs to choose the one you need.